Dipjyoti Das

We try to understand how complex behaviors emerge in biological systems at different scales of organizations, starting from the sub-cellular and cellular scale to the tissue and organismic level. At all these scales, biological systems are generally characterized by a large set of interconnected physical and chemical processes that drive the system out of equilibrium. Our method of investigation of such systems is theoretical and computational model building (using tools of statistical physics) and data analysis, in close collaboration with experimental biologists. Some specific areas of interest include: (1) Biophysics and tissue mechanics in embryonic developmental processes, (2) Stochastic dynamics of cytoskeletal filaments and molecular motors, (3) Stochastic gene expression, (4) Population dynamics of interacting micro-organisms, (5) Models of intracellular transport, and (6) Pattern formation in biology.

• PhD (Physics), IIT Bombay, 2014
• MSc (Physics), IIT Bombay, 2009
• BSc (Physics), Jadavpur University, 2007

• Assistant Professor, IISER-Kolkata ( Jan, 2019 - )
• Visiting Professor, University of Calgary (Nov 2022 - May 2023)
• Post-doctoral Associate, Yale University (Nov 2014 - Dec 2018)

• SERB International Research Experience (SIRE) Fellowship, 2022.
• Ramalingaswami Re-entry Fellowship from Department of Biotechnology (Government of India), 2019.

Research Scholars

Postdoctoral Fellows

1. R Adhikary, A Roy, M Jolly, and Dipjyoti Das*, “Effects of microRNA-mediated negative feedback on gene expression noise”, BioRxiv 2023 (https://doi.org/10.1101/2022.11.09.515756)
2. S Satheesan, B Banerjee, Dipjyoti Das*, “Effects of random hydrolysis on biofilament length distributions in a shared subunit pool” Biophysical Journal 121 (3), 502-514, 2022.
3. S Gupta, S Ray, A Khan, A China, Dipjyoti Das*, AI Mallick*, “The cost of bacterial predation via type VI secretion system leads to predator extinction under environmental stress”, iScience 24 (12), 103507, 2021.
4. S Choubey, Dipjyoti Das, S Majumdar, “Cell-to-cell variability in organelle abundance reveals mechanisms of organelle biogenesis”, Physical Review E 100 (2), 022405, 2019.
5. Dipjyoti Das, Dorthe Julich, Jamie Schwendinger-Schreck, Andrew Lawton, et al., “Organization of embryonic morphogenesis via mechanical information”, Developmental Cell 49 (6), 829-839. e5, 2019.
6. Dipjyoti Das, Veena Chatti, Scott A. Holley, and Thierry Emonet “Patterned Disordered Cell Motion Ensures Vertebral Column Symmetry”, Developmental Cell 42(2), 170-180, 2017.

• Warden, Nivedita Hostel, IISER Kolkata Campus
• Departmental UGAC Convenor (2021-2022)